Sulfonamide-containing copper(<scp>ii</scp>) complexes: new insights on biophysical interactions and antibacterial activities
Douglas Hideki Nakahata, Raphael Enoque Ferraz de Paiva, Wilton R. Lustri, Pedro P. Corbi
Abstract
Cu–(N^N)–sulfonamide complexes are selective metallonucleases that bind tightly to BSA with no protease activity. These compounds have promising antibacterial properties.
Topics & Concepts
ChemistrySulfonamideCopperAntibacterial activityCombinatorial chemistryNanotechnologyBiophysicsStereochemistryBacteriaOrganic chemistryGeneticsBiologyMaterials scienceMetal complexes synthesis and propertiesTrace Elements in HealthHIV/AIDS drug development and treatment