Radix Polygalae extract exerts antidepressant effects in behavioral despair mice and chronic restraint stress-induced rats probably by promoting autophagy and inhibiting neuroinflammation
Zhou Yunfeng, Mingzhu Yan, Ruile Pan, Zhi Wang, Tao Xue, Chenchen Li, Tianji Xia, Xinmin Liu, Qi Chang
Topics & Concepts
Behavioural despair testOpen fieldAutophagyAntidepressantPrefrontal cortexNeuroinflammationMedicinePharmacologyElevated plus mazeProinflammatory cytokineEndocrinologyInternal medicineMicrogliaHippocampusChemistryAnxietyInflammationApoptosisPsychiatryBiochemistryCognitionTryptophan and brain disordersPharmacological Receptor Mechanisms and EffectsMedicinal Plant Extracts Effects