Multilevel categoric factorial design for optimization of raloxifene hydrochloride solid dispersion in PVP K30 by hot-melt extrusion technology
Rasha M. Elkanayati, Sundus Omari, Ahmed Adel Ali Youssef, Mashan Almutairi, Ahmed Almotairy, Michael A. Repka, Eman A. Ashour
Topics & Concepts
Differential scanning calorimetrySolubilityDissolutionBioavailabilityMaterials scienceFactorial experimentPolyvinylpyrrolidoneExtrusionChemical engineeringChromatographyChemistryNuclear chemistryOrganic chemistryPharmacologyPolymer chemistryComposite materialMathematicsMedicineEngineeringThermodynamicsStatisticsPhysicsDrug Solubulity and Delivery SystemsCrystallization and Solubility StudiesProtein purification and stability