Update on human genetic susceptibility to COVID-19: susceptibility to virus and response
Vito Luigi Colona, Vasilis Vasiliou, Jessica Watt, Giuseppe Novelli, Juergen Reichardt
Abstract
[Extract] Over the past year and a half, SARS-CoV-2, the etiological agent of the COVID-19 pandemic, led to a total of almost 200 million cases, causing more than 4 million of deaths globally (Johns Hopkins University, CSSE). While we are facing rising daily hospitalizations https://ourworldindata.org/covid-hospitalizations, accessed on July 31, 2021), attributable to novel emerging variants of the virus, we also observe a decrease in both hospitalizations due to severe forms of the disease and deaths in several parts of the world, thanks to the launch of massive vaccination campaigns. To date, 4 billion vaccine doses have been administered.
Topics & Concepts
Human geneticsCoronavirus disease 2019 (COVID-19)BiologyVirology2019-20 coronavirus outbreakGeneticsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirusComputational biologyMedicineGeneInfectious disease (medical specialty)OutbreakDiseasePathologySARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studiesvaccines and immunoinformatics approaches