6-shogaol is a potential treatment for Head and Neck Squamous Cell Carcinoma
Cheng‐Ming Hsu, Hui‐Chen Su, Ming‐Yu Yang, Yao‐Te Tsai, Ming‐Shao Tsai, Yao‐Hsu Yang, Ching‐Yuan Wu, Shun‐Fu Chang
Abstract
Our data provided new insights to understand the potential pharmaceutical efficacy of a ginger derivate, 6-shogaol, in antagonizing HNSCC survival. The present study suggests that 6-shogaol is a potential novel candidate for anti-HNSCCs therapy.
Topics & Concepts
ApoptosisHead and neck squamous-cell carcinomaFlow cytometryCell cycleAnnexinChemistryp38 mitogen-activated protein kinasesCisplatinCancer researchCellWestern blotMTT assayCancerMAPK/ERK pathwayKinaseMedicineHead and neck cancerBiologyMolecular biologyBiochemistryInternal medicineChemotherapyGeneGinger and Zingiberaceae researchHedgehog Signaling Pathway Studies