Asymmetric synthesis of bedaquiline based on bimetallic activation and non-covalent interaction promotion strategies
Feng Gao, Jing Li, Tanveer Ahmad, Yicong Luo, Zhenfeng Zhang, Qianjia Yuan, Xiaohong Huo, Tao Song, Wanbin Zhang
Topics & Concepts
BedaquilineStereocenterBimetallic stripCombinatorial chemistryFood and drug administrationChemistryEnantioselective synthesisStereochemistryTuberculosisPharmacologyCatalysisOrganic chemistryMedicineMycobacterium tuberculosisPathologyAsymmetric Hydrogenation and CatalysisAsymmetric Synthesis and CatalysisCoordination Chemistry and Organometallics