Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication
Mathew V. Jones, Camille Gelot, Stephanie Munk, Amnon Koren, Yoshitaka Kawasoe, Kelly A. George, Ruth E. Santos, Jesper V. Olsen, Steven A. McCarroll, Mark G. Frattini, Tatsuro Takahashi, Prasad V. Jallepalli
Topics & Concepts
BiologyG2-M DNA damage checkpointCyclin-dependent kinaseXenopusCell biologyPhosphoproteomicsDNA replicationProtein subunitKinaseGeneticsGenomeComputational biologyDNACell cycle checkpointCell cycleGeneProtein kinase AProtein phosphorylationDNA Repair MechanismsGenomics and Chromatin DynamicsCRISPR and Genetic Engineering