Mapping the landscape of synthetic lethal interactions in liver cancer
Yang Chen, Yuchen Guo, Ruolan Qian, Yi‐Wen Huang, Linmeng Zhang, Jun Wang, Xiaowen Huang, Zhicheng Liu, Wenxin Qin, Cun Wang, Huimin Chen, Xuhui Ma, Dayong Zhang
Abstract
In this study, we report a comprehensive analysis of synthetic lethal interactions of liver cancer. Our findings may open new possibilities for patient-tailored therapeutic interventions in liver cancer.
Topics & Concepts
Synthetic lethalityLiver cancerCancerComputational biologyCancer researchInferenceMedicineBiologyBioinformaticsGeneMutantComputer scienceGeneticsArtificial intelligenceCancer Genomics and DiagnosticsBioinformatics and Genomic NetworksFerroptosis and cancer prognosis