<i>Lactiplantibacillus plantarum</i>CCFM1019 attenuate polycystic ovary syndrome through butyrate dependent gut–brain mechanism
Yufeng He, Liya Mei, Luyao Wang, Li Xiu, Jianxin Zhao, Hao Zhang, Wei Chen, Gang Wang
Abstract
CCFM1019 attenuated letrozole-induced PCOS symptoms in rats. A butyrate-dependent gut-brain mechanism may be involved in this protective effect.
Topics & Concepts
Polycystic ovaryOvaryEndocrine systemMechanism (biology)EndocrinologyInternal medicineMedicineButyrateBiologyHormoneInsulin resistanceObesityBiochemistryPhilosophyFermentationEpistemologyGut microbiota and healthNeuroendocrine regulation and behaviorOvarian function and disorders