Interaction of TiO<sub>2</sub> nanoparticles with lung fluid proteins and the resulting macrophage inflammatory response
Karsten M. Poulsen, Michaela C. Albright, Nicholas J. Niemuth, Robert M. Tighe, Christine K. Payne
Abstract
nanoparticles or coronas formed from serum or albumin. These experiments show that understanding the concentration and composition of the protein corona is essential for understanding the pulmonary response associated with human exposure to nanoparticles.
Topics & Concepts
LungNanoparticleMacrophageInflammationInflammatory responseTitanium dioxideCorona (planetary geology)Materials scienceProinflammatory cytokineChemistryBiophysicsChemical engineeringImmunologyNanotechnologyMedicineComposite materialBiochemistryBiologyInternal medicineIn vitroAstrobiologyVenusEngineeringInhalation and Respiratory Drug DeliveryNanoparticle-Based Drug DeliveryAdvanced Glycation End Products research