Exploration of weighting schemes based on allele frequency and annotation for weighted burden association analysis of complex phenotypes
David Curtis
Topics & Concepts
WeightingBiologyBiobankPhenotypeExomeComputational biologyAnnotationAllele frequencyGeneticsAlleleGenetic associationExome sequencingGeneAssociation testAssociation (psychology)Single-nucleotide polymorphismGenotypeMedicinePhilosophyEpistemologyRadiologyGenetic Associations and EpidemiologyGenomics and Rare DiseasesBRCA gene mutations in cancer