Pyrene and its derivatives increase lung adverse effects by activating aryl hydrocarbon receptor transcription
Mei Wang, Na Luo, Yanpeng Gao, Guiying Li, Taicheng An
Topics & Concepts
PyreneAryl hydrocarbon receptorChemistryCYP1B1Human healthMechanism of actionAdverse effectPolycyclic aromatic hydrocarbonPharmacologyIn vitroTranscription factorEnvironmental chemistryBiochemistryStereochemistryOrganic chemistryGeneBiologyEnzymeMedicineCytochrome P450Environmental healthToxic Organic Pollutants ImpactCarcinogens and Genotoxicity AssessmentMicrobial bioremediation and biosurfactants