Pd-N-heterocyclic carbene complex catalysed C–H bond activation of 2-isobutylthiazole at the C5 position with aryl bromides
Siraj Khan, Nesrin Buğday, Sedat Yaşar, Naseem Ullah, İsmaıl Özdemır
Abstract
An effective and efficient catalytic system has been reported for the synthesis of C5-arylated 2-isobutylthiazoles.
Topics & Concepts
ChemistryCarbeneArylMedicinal chemistryPosition (finance)StereochemistryCatalysisOrganic chemistryAlkylFinanceEconomicsCatalytic C–H Functionalization MethodsN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCyclopropane Reaction Mechanisms