Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export
Omkar Shinde, Joshua A. Boyer, Stephanie Cambier, Jordyn J. VanPortfliet, Xuewu Sui, Gaya P. Yadav, Elizabeth Viverette, Mario J. Borgnia, A. Phillip West, Qi Zhang, Daniel B. Stetson, Pingwei Li
Topics & Concepts
BiologyInnate immune systemTransmembrane proteinSubfamilyCell biologyATP-binding cassette transporterLigand (biochemistry)ABCC1BiochemistryReceptorTransporterGeneinterferon and immune responsesInflammasome and immune disordersImmune Response and Inflammation