Litcius/Paper detail

Designer installation of a substrate recruitment domain to tailor enzyme specificity

Rodney Park, Chayanid Ongpipattanakul, Satish K. Nair, Albert A. Bowers, Brian Kuhlman

2022Nature Chemical Biology17 citationsDOIOpen Access PDF

Topics & Concepts

Protein designEnzymeProtein engineeringSubstrate (aquarium)Active siteChemistryBiochemistryRational designProtein structureComputational biologyBiologyNanotechnologyMaterials scienceEcologyChemical Synthesis and AnalysisPeptidase Inhibition and AnalysisClick Chemistry and Applications