The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation
Yanjia Shen, Ran Yang, Jiaying Zhao, Miao Chen, Shuhan Chen, Baixi Ji, Hou‐Zao Chen, De‐Pei Liu, Li Li, Guanhua Du
Topics & Concepts
Experimental autoimmune encephalomyelitisHistone deacetylaseProinflammatory cytokinePharmacologyHistone deacetylase inhibitorMultiple sclerosisNeuroinflammationMedicineCancer researchImmunologyMyelin oligodendrocyte glycoproteinEncephalomyelitisMicrogliaCaffeic acid phenethyl esterInflammationChemistryHistoneBiochemistryCaffeic acidAntioxidantGeneHistone Deacetylase Inhibitors ResearchNF-κB Signaling PathwaysMultiple Sclerosis Research Studies