RAI14 silencing suppresses progression of esophageal cancer via the STAT3 pathway
Jianlin Wang, Yun Cai, Judong Luo, Zhiqiang Sun, Jingping Yu, Feng Yan, Xia He
Abstract
. Our results suggest that RAI14 regulates the STAT3 pathway and acts as an oncogene during EC progression.
Topics & Concepts
Downregulation and upregulationCyclin D1Gene silencingCancer researchOncogeneCell cycleGene knockdownCell growthSTAT3ApoptosisBiologyCancerCell cycle checkpointGeneGeneticsCytokine Signaling Pathways and InteractionsCancer-related Molecular Pathwaysinterferon and immune responses