Intranasal delivery of chitosan decorated nanostructured lipid carriers of Buspirone for brain targeting: Formulation development, optimization and In-Vivo preclinical evaluation
K.M. Noorulla, Mohd Yasir, Faizi Muzaffar, S Roshan, Mohammed M. Ghoneim, Alanood S. Almurshedi, Abdurazak J. Tura, Sultan Alshehri, Teshome Gebissa, Shimelis Mekit, Mohammed Muqtader Ahmed, Ameeduzzafar Zafar
Topics & Concepts
BioavailabilityBox–Behnken designIn vivoPharmacokineticsOleic acidChitosanNasal administrationSolid lipid nanoparticleMaterials sciencePulmonary surfactantPharmacologyChromatographyChemistryDrug deliveryNanotechnologyResponse surface methodologyMedicineOrganic chemistryBiochemistryBiologyBiotechnologyAdvancements in Transdermal Drug DeliveryAdvanced Drug Delivery SystemsLipid Membrane Structure and Behavior