Visible Light‐Induced Decarboxylative Peroxidation of Carboxylic Acids: Metal‐Free Synthesis of Benzyl Peroxides
Chenhao Lou, Yuting Feng, Qiuwei Huang, Leiyang Lv, Zhiping Li
Abstract
Abstract A visible light‐induced direct decarboxylative peroxidation of carboxylic acids under mild conditions has been disclosed. With this protocol, a variety of readily available carboxylic acids were converted to the peroxidation products in moderate to good yields via decarboxylative radical C−OO bond coupling. Tert ‐butyl hydroperoxide acts as both the oxidant and peroxyl source, avoiding the use of transition metals or extra oxidants.
Topics & Concepts
ChemistryDecarboxylationCarboxylic acidLipid peroxidationOrganic chemistryVisible spectrumPhotochemistryAntioxidantCatalysisPhysicsOptoelectronicsRadical Photochemical ReactionsOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization Methods