Combining CRISPRi and metabolomics for functional annotation of compound libraries
Miquel Anglada-Girotto, Gabriel Handschin, Karin Ortmayr, Adrián I. Campos, Ludovic Gillet, Pablo Manfredi, Claire V. Mulholland, Michael Berney, Urs Jenal, Paola Picotti, Mattia Zampieri
Topics & Concepts
MetabolomicsComputational biologyDrug discoverySmall moleculeBiologyCRISPRFunction (biology)Functional genomicsAnnotationGeneGenomicsGeneticsBioinformaticsGenomeCRISPR and Genetic EngineeringComputational Drug Discovery MethodsMicrobial Metabolic Engineering and Bioproduction