Hemopexin accumulates in kidneys and worsens acute kidney injury by causing hemoglobin deposition and exacerbation of iron toxicity in proximal tubules
Xiaoming Fan, Xiaolu Zhang, Lijun Liu, Shungang Zhang, Cole B. Pelger, Haroon Y. Lughmani, Steven T. Haller, William T. Gunning, Christopher J. Cooper, Rujun Gong, Lance D. Dworkin, Rajesh Gupta
Topics & Concepts
HemopexinKidneyAcute kidney injuryHemoglobinHemeMedicineToxicityPharmacologyEndocrinologyInternal medicineChemistryBiochemistryEnzymeHeme Oxygenase-1 and Carbon MonoxideHemoglobinopathies and Related DisordersNeonatal Health and Biochemistry