A British Society for Haematology Guideline: Diagnosis and management of thrombotic thrombocytopenic purpura and thrombotic microangiopathies
Marie Scully, R. Rayment, Amanda Clark, John‐Paul Westwood, Tanya Cranfield, Richard Gooding, Catherine Bagot, A. E. Taylor, Vinoth Sankar, Daniel P. Gale, Tina Dutt, J. McIntyre, Will Lester
Abstract
The objective of this guideline is to provide healthcare professionals with clear, up-to-date and practical guidance on the management of thrombotic thrombocytopenic purpura (TTP) and related thrombotic microangiopathies (TMAs), including complement-mediated haemolytic uraemic syndrome (CM HUS); these are defined by thrombocytopenia, microangiopathic haemolytic anaemia (MAHA) and small vessel thrombosis. Within England, all TTP cases should be managed within designated regional centres as per NHSE commissioning for highly specialised services.
Topics & Concepts
Thrombotic thrombocytopenic purpuraMedicineGuidelineHematologyPurpura (gastropod)Intensive care medicineSchistocytePlateletInternal medicinePathologyBiologyEcologyComplement system in diseasesRenal Diseases and GlomerulopathiesPlatelet Disorders and Treatments