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Integrated network pharmacology and experimental validation to elucidate the mechanism of celastrol in mitigating sepsis-induced acute lung injury in mice

Danli Zhu, Jinghan Zhang, Xiao‐Chun Huang, Na Wei, Jinxiu Jiang, Jiayao Li, Li Liu, Yulin Liu, Jun Zhou, Jing Jia

2025Phytomedicine10 citationsDOI

Topics & Concepts

CelastrolPharmacologyMechanism (biology)SepsisMedicineChemistryImmunologyBiochemistryApoptosisPhilosophyEpistemologyNatural Compounds in Disease TreatmentCell death mechanisms and regulationAndrographolide Research and Applications
Integrated network pharmacology and experimental validation to elucidate the mechanism of celastrol in mitigating sepsis-induced acute lung injury in mice | Litcius