Design of Mesoporous Silica Nanoparticles for the Treatment of Amyotrophic Lateral Sclerosis (ALS) with a Therapeutic Cocktail Based on Leptin and Pioglitazone
Diana Díaz‐García, Águeda Ferrer-Donato, José M. Méndez‐Arriaga, Marta Cabrera-Pinto, Miguel Díaz‐Sánchez, Sanjiv Prashar, CM Fernandez-Martos, Santiago Gómez‐Ruiz
Abstract
and the usefulness of their use in neurodegenerative models, including ALS.
Topics & Concepts
Amyotrophic lateral sclerosisPioglitazoneMesoporous silicaIn vivoNeuroprotectionLeptinNanocarriersPharmacologyNanomedicineMedicineDrugDiseaseType 2 diabetesChemistryInternal medicineDiabetes mellitusMaterials scienceNanotechnologyBiologyNanoparticleMesoporous materialEndocrinologyObesityBiochemistryCatalysisBiotechnologyAmyotrophic Lateral Sclerosis Researchbiodegradable polymer synthesis and propertiesAlzheimer's disease research and treatments