Design, synthesis, and biological evaluation of novel 4H-chromen-4-one derivatives as antituberculosis agents against multidrug-resistant tuberculosis
Wenting Zhao, Bin Wang, Yuke Liu, Lei Fu, Sheng Li, Hongyi Zhao, Yu Lu, Dongfeng Zhang
Topics & Concepts
ChemistryDruggabilityBenzofuranCytotoxicityPharmacologyIn vivoBioavailabilityMultiple drug resistanceLead compoundTuberculosisDrugCombinatorial chemistryIn vitroStereochemistryBiochemistryAntibioticsMedicineBiotechnologyBiologyPathologyGeneTuberculosis Research and EpidemiologyHIV/AIDS drug development and treatmentCancer therapeutics and mechanisms