Peptide-assembled nanoparticles targeting tumor cells and tumor microenvironment for cancer therapy
Meichen Zhang, Haiyan Xu
Abstract
non-covalent bond, which have presented appealing as well as enhanced capacities of recognizing targeted cells, responding to microenvironments, mediating internalization, and achieving therapeutic effects. In this review, we will introduce the peptide-based nanoparticles and their application advances in targeting tumor cells and stromal cells, including suppressive immune cells, fibrosis-related cells, and angiogenic vascular cells, for cancer therapy.
Topics & Concepts
Tumor microenvironmentPeptideCancer researchCancer therapyCancerTumor cellsNanoparticleChemistryNanotechnologyMedicineMaterials scienceBiochemistryInternal medicineNanoplatforms for cancer theranosticsRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniques