Litcius/Paper detail

Blocking HOTAIR protects human chondrocytes against IL-1β-induced cell apoptosis, ECM degradation, inflammatory response and oxidative stress via regulating miR-222-3p/ADAM10 axis

Jinliang Wang, Xiaofei Luo, Songtao Cai, Jing‐Tao Sun, Shaohua Wang, Xuan Wei

2021International Immunopharmacology37 citationsDOI

Topics & Concepts

HOTAIRChemistryMolecular biologySmall interfering RNAMatrix metalloproteinaseGene knockdownSuperoxide dismutaseOxidative stressType II collagenCancer researchApoptosisDownregulation and upregulationCell biologyBiologyCell cultureCartilageTransfectionLong non-coding RNABiochemistryGeneticsAnatomyGeneOsteoarthritis Treatment and MechanismsCancer-related molecular mechanisms researchRheumatoid Arthritis Research and Therapies