ALKBH5-mediated m6A demethylation of FOXM1 mRNA promotes progression of uveal melanoma
Lili Hao, Jiayang Yin, Hong Yang, Chaoxuan Li, Linxin Zhu, Lian Liu, Jingxiang Zhong
Abstract
mRNA promotes UM progression. Therefore, AKLBH5 is a potential prognostic biomarker and therapeutic target in UM.
Topics & Concepts
MelanomaDemethylationMessenger RNACancer researchFOXM1BiologyMedicineInternal medicineCancerGeneticsGene expressionGeneDNA methylationCell cycleRNA modifications and cancerHVDC Systems and Fault ProtectionPeptidase Inhibition and Analysis