Encapsulation of a small-molecule drug based on substituted 2-aminothiophenes in calcium carbonate carriers for therapy of melanoma
Timofey E. Karpov, Anna Rogova, Darya R. Akhmetova, Yulia A. Tishchenko, Anastasia V. Chinakova, D. V. Lipin, Nina V. Gavrilova, I. A. Gorbunova, Sergei A. Shipilovskikh, Alexander S. Timin
Abstract
toxicity towards major organs such as heart, lung, liver, kidney, and spleen. Thus, this work provided an efficient strategy for the improved chemotherapy of solid tumors by using an encapsulated form of small molecule drugs.
Topics & Concepts
ChemistryCalcium carbonateCalciumEncapsulation (networking)MelanomaMoleculeDrugSmall moleculeBiophysicsCombinatorial chemistryPhotochemistryCancer researchPharmacologyBiochemistryOrganic chemistryMedicineBiologyComputer networkComputer scienceSynthesis and Characterization of Heterocyclic CompoundsSynthesis and Reactivity of Sulfur-Containing CompoundsSynthesis and biological activity