Newborn Dried Blood Spots for Serologic Surveys of COVID-19
Feimei Liu, Mytien Nguyen, Pavithra Vijayakumar, Alanna R. Kaplan, Amit Meir, Yile Dai, Eric Y. Wang, Hannah Walsh, Aaron M. Ring, Saad B. Omer, Shelli Farhadian
Abstract
There is an urgent need for inexpensive, population-wide surveillance testing for COVID-19. We tested newborn dried blood spot (DBS) anti-SARS-CoV-2 antibodies for all infants born at Yale from March to May 2020, and found that newborn DBS serologies reflect maternal and population-wide infection rates during the study period. This suggests a role for DBS in COVID-19 surveillance in areas where viral testing is limited.
Topics & Concepts
Dried bloodSerologyCoronavirus disease 2019 (COVID-19)Dried blood spotSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PopulationMedicine2019-20 coronavirus outbreakVirologyPediatricsAntibodyImmunologyEnvironmental healthBiologyOutbreakInternal medicineDiseaseInfectious disease (medical specialty)GeneticsChromatographyChemistrySARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testingCOVID-19 Impact on Reproduction