circEYA1 Functions as a Sponge of miR-582-3p to Suppress Cervical Adenocarcinoma Tumorigenesis via Upregulating CXCL14
Junfen Xu, Yanan Zhang, Yongjie Huang, Xiaohui Dong, Zhenzhen Xiang, Jian Zou, Luyao Wu, Weiguo Lü
Abstract
. In addition, the expression, correlation, and clinical diagnostic value of circEYA1/miR-582-3p/CXCL14 were confirmed in 198 clinical cervical tissue samples. In summary, our findings highlight a novel tumor suppressive role of circEYA1 in cervical adenocarcinoma tumorigenesis and may provide a potential diagnostic marker and therapeutic target for patients with cervical adenocarcinoma.
Topics & Concepts
CarcinogenesisAdenocarcinomamicroRNACancer researchBiologyGeneCancerGeneticsCircular RNAs in diseasesMicroRNA in disease regulationCancer-related molecular mechanisms research