Distinct placental molecular processes associated with early-onset and late-onset preeclampsia
Zhonglu Ren, Yunfei Gao, Yue Gao, Guanmei Liang, Qian Chen, Sijia Jiang, Xiaoxue Yang, Cui-Xia Fan, Haizhen Wang, Jing Wang, Yi‐Wu Shi, Chaoqun Xiao, Mei Zhong, Xinping Yang
Abstract
These results suggest that early-onset and late-onset severe preeclampsia have different molecular mechanisms, whereas the late-onset mild preeclampsia may have no placenta-specific causal factors. A few regulators may be the key drivers of the dysregulated molecular pathways.
Topics & Concepts
PreeclampsiaMedicineAge of onsetInternal medicinePregnancyBiologyDiseaseGeneticsPregnancy and preeclampsia studiesBirth, Development, and HealthMicroRNA in disease regulation