Design, synthesis, and anti-proliferative evaluation of new quinazolin-4(3H)-ones as potential VEGFR-2 inhibitors
Khaled El‐Adl, Abdel‐Ghany A. El‐Helby, Rezk R. Ayyad, Hazem A. Mahdy, Mohamed M. Khalifa, H. El-Nagar, Ahmed B. M. Mehany, Ahmed M. Metwaly, Mostafa A. Elhendawy, Mohamed M. Radwan, Mahmoud A. ElSohly, Ibrahim H. Eissa
Topics & Concepts
ChemistryCytotoxicitySorafenibDoxorubicinMTT assayIn vitroQuinazolineCytotoxic T cellPharmacologyDocking (animal)Cell cultureStereochemistryBiochemistryCancer researchChemotherapyInternal medicineBiologyNursingGeneticsHepatocellular carcinomaMedicineQuinazolinone synthesis and applicationsSynthesis and Biological EvaluationSynthesis and biological activity