Management of cardiac fibrosis is the largest unmet medical need in heart failure

Abstract

Cardiac fibrosis is a major driver associated with the growing burden of heart failure, especially in older people. However, integrating cardiac fibrosis in heart failure management is still an unmet medical need, which may be explained by its high tissue heterogeneity and clinical diversity, and, as a consequence, the very real limitations of its diagnosis and treatment. In this viewpoint article we summarize the challenges and requirements in the clinical management of cardiac fibrosis in heart failure patients.

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