Single-cell RNA sequencing reveals that HSD17B2 in cancer-associated fibroblasts promotes the development and progression of castration-resistant prostate cancer
Yunyan Zhang, Aoyu Fan, Yunpeng Li, Zhuolin Liu, Yu Liu, Jianming Guo, Jun Hou, Xiaobo Li, Wei Chen, Wei Chen
Topics & Concepts
Prostate cancerCancer researchCancer-Associated FibroblastsTumor microenvironmentBiologyGene knockdownCancerCellDihydrotestosteroneCancer cellTumor progressionCell cultureEndocrinologyAndrogenHormoneGeneticsTumor cellsCancer Immunotherapy and BiomarkersProstate Cancer Treatment and ResearchCancer Cells and Metastasis