Effect of excipient particle size distribution variability on compact tensile strength; and its in-line prediction by force-displacement and force-time profiling
Wee Beng Lee, Effendi Widjaja, Paul Wan Sia Heng, Lai Wah Chan
Topics & Concepts
Ultimate tensile strengthMicrocrystalline celluloseMaterials scienceComposite materialExcipientCompactionProcess analytical technologyChemistryChromatographyCelluloseEngineeringChemical engineeringBioprocessDrug Solubulity and Delivery SystemsGranular flow and fluidized bedsProtein purification and stability