HDAC inhibition regulates oxidative stress in CD4+Thelper cells of chronic obstructive pulmonary disease and non-small cell lung cancer patients via mitochondrial transcription factor a (mtTFA) modulating NF-κB/HIF1α axis
Geetha Shanmugam, Krishnaveni Subramaniyam, Melvin George, Koustav Sarkar
Topics & Concepts
Trichostatin AEpigeneticsHistone deacetylaseCancer researchLung cancerTFAMBiologyCOPDEpigenetic therapyHistone deacetylase inhibitorInflammationImmunologyCancerHistoneMedicineMitochondrionDNA methylationGene expressionPathologyInternal medicineCell biologyMitochondrial biogenesisGeneticsGeneHistone Deacetylase Inhibitors ResearchEpigenetics and DNA MethylationSirtuins and Resveratrol in Medicine