Δ133p53α Protects Human Astrocytes from Amyloid-beta Induced Senescence and Neurotoxicity
Kyra Ungerleider, Jessica A. Beck, Delphine Lissa, Sebastien M. Joruiz, Izumi Horikawa, Curtis C. Harris
Topics & Concepts
SenescenceProinflammatory cytokineNeurodegenerationCell biologyAstrocyteBiologyDownregulation and upregulationDNA damageContext (archaeology)Amyloid betaNeurotoxicityImmunologyNeuroscienceInflammationChemistryMedicineBiochemistryCentral nervous systemPathologyToxicityDiseaseGeneDNAPeptidePaleontologyOrganic chemistryAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsTelomeres, Telomerase, and Senescence