Phase 3 Randomized Trial of Prophylactic Cranial Irradiation With or Without Hippocampus Avoidance in SCLC (NCT01780675)
J. Belderbos, Dirk K.M. De Ruysscher, Katrien De Jaeger, Friederike Koppe, Maarten Lambrecht, Yolande Lievens, Edith Dieleman, Jaap Jaspers, Jan P. van Meerbeeck, Fred Ubbels, Margriet Kwint, Marianne A. Kuenen, Sabine Deprez, Michiel B. de Ruiter, Willem Boogerd, Karolina Sikorska, Harm van Tinteren, Sanne B. Schagen
Topics & Concepts
MedicineConventional PCIProphylactic cranial irradiationNeurocognitiveConfidence intervalRandomized controlled trialClinical endpointCumulative incidenceIncidence (geometry)NeuropsychologyInternal medicineSurgeryCognitionTransplantationPsychiatryPhysicsOpticsMyocardial infarctionLung Cancer Research StudiesBrain Metastases and TreatmentCancer-related cognitive impairment studies