Molecular hybrid of 1,2,3-triazole and schiff base as potential antibacterial agents: DFT, molecular docking and ADME studies
Yonas Belay, Alfred Muller, Paballo Leballo, Oyebamiji A. Kolawole, Adedapo S. Adeyinka, Thierry Y. Fonkui, Lesetja R. Motadi
Topics & Concepts
ChemistryADMECombinatorial chemistrySchiff baseAntibacterial activityDocking (animal)StereochemistryRhodanineKlebsiella pneumoniaActive siteCarbon-13 NMRTriazoleEscherichia coliOrganic chemistryBacteriaBiochemistryEnzymeIn vitroMedicineGeneticsNursingBiologyGeneSynthesis and biological activityClick Chemistry and ApplicationsSynthesis and Characterization of Heterocyclic Compounds