Using sodium acetate for the synthesis of [Au(NHC)X] complexes
Thomas Scattolin, Nikolaos V. Tzouras, Laura Falivene, Luigi Cavallo, Steven P. Nolan
Abstract
The role of sodium acetate in the synthesis of [Au(NHC)Cl] complexes was examined. The use of this base was also investigated for the activation of C-H and S-H bonds by experimental and computational methods. The synthetic use of NaOAc to assemble these complexes is applicable to a wide range of NHCs and proceeds under air, under mild conditions and using technical grade green solvents.
Topics & Concepts
Sodium acetateSodiumChemistryCombinatorial chemistryNuclear chemistryMedicinal chemistryOrganic chemistryN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling ReactionsCarbon dioxide utilization in catalysis