An efficient transition-metal-free route to quinazolin-4(3<i>H</i>)-ones <i>via</i> 2-aminobenzamides and thiols
Yibo Dong, Jinli Zhang, Jinchen Yang, Congcong Yan, Yangjie Wu
Abstract
An efficient approach to quinazolin-4(3 H )-ones was developed by a one-pot intermolecular annulation reaction of o -amino benzamides and thiols.
Topics & Concepts
ChemistryAnnulationIntermolecular forceTransition metalCombinatorial chemistryStereochemistryMedicinal chemistryOrganic chemistryMoleculeCatalysisQuinazolinone synthesis and applicationsAdvanced Synthetic Organic ChemistryPhenothiazines and Benzothiazines Synthesis and Activities