Engineering chimeric diterpene synthases and isoprenoid biosynthetic pathways enables high-level production of miltiradiene in yeast
Tianyuan Hu, Jiawei Zhou, Yuru Tong, Ping Su, Xinlin Li, Yuan Liu, Nan Liu, Xiaoyi Wu, Yifeng Zhang, Jiadian Wang, Linhui Gao, Lichan Tu, Yun Lü, Zhouqian Jiang, Yongjin J. Zhou, Wei Gao, Luqi Huang
Topics & Concepts
DiterpeneMetabolic engineeringGeranylgeraniolSalvia miltiorrhizaBiosynthesisBiochemistryYeastTerpenoidBiologyBiorefineryCarnosic acidEnzymeBiotechnologyAntioxidantPathologyBiofuelAlternative medicineMedicineTraditional Chinese medicinePlant biochemistry and biosynthesisMicrobial Natural Products and BiosynthesisNatural product bioactivities and synthesis