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Ameliorate impacts of scopoletin against vancomycin-induced intoxication in rat model through modulation of Keap1-Nrf2/HO-1 and IκBα-P65 NF-κB/P38 MAPK signaling pathways: Molecular study, molecular docking evidence and network pharmacology analysis

Marwa M. Khalaf, Samar M. Hassan, Ahmed M. Sayed, Amira M. Abo‐Youssef

2021International Immunopharmacology32 citationsDOI

Topics & Concepts

NephrotoxicityOxidative stressScopoletinPharmacologyp38 mitogen-activated protein kinasesKEAP1NF-κBKidneyChemistryMAPK/ERK pathwayBiochemistryMedicineInternal medicineSignal transductionPathologyTranscription factorAlternative medicineGeneGenomics, phytochemicals, and oxidative stressVitamin C and Antioxidants ResearchDrug-Induced Hepatotoxicity and Protection
Ameliorate impacts of scopoletin against vancomycin-induced intoxication in rat model through modulation of Keap1-Nrf2/HO-1 and IκBα-P65 NF-κB/P38 MAPK signaling pathways: Molecular study, molecular docking evidence and network pharmacology analysis | Litcius