Binding of combined irinotecan and epicatechin to a pH-responsive DNA tetrahedron for controlled release and enhanced cytotoxicity
Lu Wang, Yushu Wu, Tianxin Weng, Xinyu Li, Xinpeng Zhang, Yanqing Zhang, Lixia Yuan, Yongfang Zhang, Min Liu
Topics & Concepts
ChemistryCytotoxicityIrinotecanCamptothecinIn vitroBiophysicsCancer cellDNANuclear chemistryBiochemistryColorectal cancerCancerMedicineInternal medicineBiologyAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryDrug Transport and Resistance Mechanisms