Optimization of medium composition to increase the expression of recombinant human interferon-β using the Plackett–Burman and central composite design in E. coli SE1
Dharam Pal, Gopal Patel, Prakashkumar Dobariya, Shivraj Hariram Nile, Abhay H. Pande, Uttam Chand Banerjee
Topics & Concepts
Recombinant DNACentral composite designResponse surface methodologyEscherichia coliGrowth mediumComposition (language)Plackett–Burman designChemistryFood scienceMolecular biologyGeneBiologyBiochemistryChromatographyBacteriaGeneticsLinguisticsPhilosophyViral Infectious Diseases and Gene Expression in InsectsMonoclonal and Polyclonal Antibodies ResearchProtein purification and stability