Litcius/Paper detail

Amine functionalized magnetic resorcinol formaldehyde as a green and reusable nanocatalyst for the Knoevenagel condensation

Paria Dehghani, Dawood Elhamifar, Shiva Kargar

2025Scientific Reports13 citationsDOIOpen Access PDF

Abstract

Herein, a novel amine-functionalized magnetic resorcinol-formaldehyde with a core-shell structure (Fe 3 O 4 @RF/Pr-NH 2 ) is prepared through the chemical immobilization of (3-aminopropyl)trimethoxysilane over Fe 3 O 4 @RF composite. Characterization through FT-IR, EDX, PXRD, and TGA confirmed successful surface modification while preserving the crystalline structure of Fe 3 O 4 . The VSM analysis demonstrated excellent superparamagnetic properties, and SEM and TEM images revealed spherical particles for the designed nanocatalyst. The Fe 3 O 4 @RF/Pr-NH 2 nanocomposite was employed as a robust nanocatalyst to promote the Knoevenagel condensation of benzaldehydes with ethyl cyanoacetate and malononitrile, resulting in the formation of substituted olefins. Various aromatic aldehydes were used as substrates in the presence of 0.01 g of Fe 3 O 4 @RF/Pr-NH 2 , achieving high to excellent yields (87–97%) within short reaction times (10–50 min) in EtOH at 60 °C. The high performance of Fe 3 O 4 @RF/Pr-NH 2 is attributed to the hydrophobic nature of RF shell, which facilitates the accumulation of organic precursors around the catalytic active sites and enhances product yields. The designed magnetic catalyst could retain its high efficiency for at least ten runs. The metal-free, low-cost, and environmentally friendly attributes of the Fe 3 O 4 @RF/Pr-NH 2 catalyst make it a promising alternative to traditional metal-based catalysts.

Topics & Concepts

Knoevenagel condensationFormaldehydeResorcinolAmine gas treatingChemistryGreen chemistryCondensationOrganic chemistryMagnetic nanoparticlesCombinatorial chemistryMaterials scienceNanotechnologyNanoparticleCatalysisReaction mechanismPhysicsThermodynamicsMulticomponent Synthesis of HeterocyclesChemical Synthesis and ReactionsPolyoxometalates: Synthesis and Applications