Encoded hydrogel microparticles with universal mismatch-incorporated DNA probes for highly specific multiplex detection of SNPs
Hyun June Moon, Seok Joon Mun, Jun Ho Lee, Yoon Ho Roh, Yong Jun Lim, Ki Wan Bong
Topics & Concepts
MultiplexChemistryHybridization probeMicroparticleDNANucleic acidDuplex (building)Single-nucleotide polymorphismOligonucleotideBase pairNucleic acid thermodynamicsMultiplex ligation-dependent probe amplificationComputational biologyNanotechnologyGeneticsBase sequenceGeneBiologyBiochemistryGenotypeMaterials scienceExonAstrobiologyAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryBiosensors and Analytical Detection