Platin-<i>C</i> containing nanoparticles: a recipe for the delivery of curcumin–cisplatin combination chemotherapeutics to mitochondria
Bhabatosh Banik, Akash Ashokan, Joshua H. Choi, Bapurao Surnar, Shanta Dhar
Abstract
incorporated targeting NPs in attenuating cellular inflammatory markers by utilizing the curcumin component. This study advances our understanding of the cisplatin prodrug approach to combine chemotherapeutic and inflammatory effects in accessing combinatory pathways.
Topics & Concepts
ProdrugCurcuminCisplatinChemistryDrug deliveryPlatinumCombinatorial chemistryDrugNanoparticleCancer cellNanotechnologyPharmacologyCancerBiochemistryMaterials scienceOrganic chemistryChemotherapyCatalysisMedicineSurgeryInternal medicineCurcumin's Biomedical ApplicationsNanoparticle-Based Drug DeliveryRetinoids in leukemia and cellular processes