Targeting endothelial glycolytic reprogramming by tsRNA-1599 for ocular anti-angiogenesis therapy
Xiaoyan Han, Lingjie Kong, Duo Li, Ming Tong, Xiu‐Miao Li, Chen Zhao, Qin Jiang, Biao Yan
Abstract
Targeting glycolytic reprogramming of endothelial cells by a tRNA-derived small RNA represents an exploitable therapeutic approach for ocular neovascular diseases.
Topics & Concepts
ReprogrammingAngiogenesisGlycolysisCancer researchChemistryMedicineBiologyBiochemistryMetabolismCellCorneal Surgery and TreatmentsRNA Interference and Gene DeliveryMicroRNA in disease regulation